N-methyl-D-aspartic acid receptor structure and function

Citation metadata

Authors: C.J. McBain and M.L. Mayer
Date: July 1994
From: Physiological Reviews(Vol. 74, Issue 3)
Publisher: American Physiological Society
Document Type: Article
Length: 11,800 words

Main content

Abstract :

Recent studies reveal that N-methyl-D-aspartic acid (NMDA) receptors are more complex than previously thought. It appears that NMDA receptor subunits have amino acid sequences that are highly similar to those of ligand-gated ion channels. This suggests that these two possess common structural patterns. The activity of NMDA receptors are regulated by allosteric mechanisms as well as several second messenger systems and interactions with the cytoskeleton.

Source Citation

Source Citation
McBain, C.J., and M.L. Mayer. "N-methyl-D-aspartic acid receptor structure and function." Physiological Reviews, vol. 74, no. 3, July 1994, pp. 723+. link.gale.com/apps/doc/A15672233/AONE?u=null&sid=googleScholar. Accessed 2 Oct. 2023.

Gale Document Number: GALE|A15672233