Psychiatric symptoms as a clinical presentation of Cushing's disease--case report--/Manifestari psihiatrice in boala Cushing --prezentare de caz--

The clinical presentation of Cushing's disease reflects chronic cortisol excess, and in the majority of the patients, it includes a broad spectrum of psychological or psychiatric manifestations. We present a case that reflects the importance of multidisciplinary approach of a patient with an endocrinology problem, as well as the possible correlation between high levels of plasmatic/urinary cortisol and the psychiatric symptoms. KEYWORDS Cushing's disease, hypercortisolism, ACTH, depression Manifestarile clinice ale sindromului Cushing sunt expresia excesului de cortizol de lunga durata, la majoritatea pacientilor fiind prezent un spectru larg de simptome din sfera psihiatriei. Vom prezenta, in cele ce urmeaza, un caz clinic ce demonstreaza importanta abordarii multidisciplinare a pacientului cu afectiuni endocrinologice, precum si posibila legatura intre nivelurile crescute de cortizol plasmatic/urinar si simptomatologia psihiatrica. CUVINTE-CHEIE boala Cushing, hipercortizolism, ACTH, depresie