Anti-inflammatory effects of DHA compared to EPA
Allaire J, Couture P, Leclerc M, Charest A, Marin J, Lepine MC et al. 2016. Randomized, crossover, head-to-head comparison of EPA and DHA supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA Study. AJCN. In print: doi: 10.3945/ajcn.116.131.896
Sub-clinical inflammation is recognised as a key factor in the development of atherosclerosis and progression to ischaemic heart disease. Whilst there is a growing body of research suggesting long chain [omega]-3 (n-3) polyunsaturated fatty acids (PUFAs) may reduce the proinflammatory state associated with obesity and metabolic syndrome, most studies investigating the anti-inflammatory effects have used varying combinations of eicosapentanoic acid (EPA) and docohexaenoic acid (DHA). The current study aimed to compare the individual effects of EPA supplementation with DHA supplementation on inflammatory markers and blood lipids in men and women at risk of cardiovascular disease (CVD).
The Canadian trial was a double-blind, randomised, crossover, controlled study conducted in individuals with abdominal obesity ([greater than...
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