Comparative Efficacy of Piperazine, Ivermectin and Levamisole in Spontaneous Toxocariasis in Canines based on Faecal Egg Count and Haemato-biochemical changes

The present study was undertaken to assess the efficacy of three drugs viz. Piperazine, Ivermectin and Levamisole against Toxocara canis. A total of 121 dogs were screened for natural infection of Toxocara canis, out of which 24 dogs were found positive which were randomly categorized into four groups (A, B, C, and D) including control. Therapeutic trials were conducted to evaluate the clinical efficacy of Piperazine (200 mg/kg b. wt.), Ivermectin (0.2 mg/kg b. wt.) and Levamisole (7.5mg/kg b. wt.) in terms of reduction in the number of eggs discharged in the faeces (EPGF) and variation in haemato-biochemical parameters post treatment. Results showed that Piperazine, Ivermectin and Levamisole produce significantly different (p Keywords: Dog; egg per gram of faeces (EPGF); ivermectin; levamisole; piperazine; Toxocara canis.