Hodgkin lenfomali bir hastada varyant Guillain-Barre sendromu: AMSAN/Variant Guillain-Barre syndrome in a patient with Hodgkin lymphoma: AMSAN.

Citation metadata

Authors: Isik Odaman Al, Basak Koç, Cengiz Bayram, Ezgi Uysalol Pasli, Edibe Pembegül Yildiz and Ali Ayçiçek
Date: Dec. 2018
From: Turkish Pediatrics Archive(Vol. 53, Issue 4)
Publisher: AVES
Document Type: Case study; Report
Length: 2,137 words

Main content

Abstract :

Lenfomalar, lenfoid kökenli hücrelerin anormal çogalmasi sonucu ortaya çikan tümörlerdir. Hodgkin lenfomada nörolojik bulgular; sinir sistemine yayilim, kemoterapi ve radyoterapiye ikincil, kitle basisi sonucu, enfeksiyon ile iliskili olarak ya da paraneoplastik sendrom seklinde ortaya çikabilir. Paraneoplastik nörolojik sendromlar Hodgkin ve Hodgkin-disi lenfomalarda nadiren görülür. Hodgkin lenfomada görülen serebellar sendrom ve dermato-polimiyozit disinda diger paraneoplastik nörolojik bulgular olgu bildirimi düzeyindedir. Bu yazida Hodgkin lenfoma tanisi ile izledigimiz, tedavi baslama asamasinda iken her iki alt ekstremitelerden baslayan güçsüzlük ve duyu kaybi gelisen, klinik bulgularina ve yapilan tetkiklerine dayanarak Guillain-Barre sendromunun bir alt tipi olan akut motor duyusal aksonal nöropati tanisi alan bir olgu sunulmustur. Anahtar sözcükler: Guillain-Barre sendromu, Hodgkin lenfoma, paraneoplastik sendrom Lymphomas are solid tumors characterized by the malignant proliferation of lymphoid cells. Neurologic signs encountered in patients with Hodgkin's lymphoma can be due to the direct spread of tumor to the nervous system, secondary to chemotherapy or radiation, secondary to tumor mass compression, infectious causes and paraneoplastic syndromes. Paraneoplastic neurologic syndromes are rarely encountered in patients with Hodgkin's lymphoma and non-Hodgkin's lymphoma. Except for paraneoplastic cerebellar degeneration in Hodgkin's lymphoma and dermato/polymyositis in both Hodgkin's lymphoma and non-Hodgkin's lymphoma, other paraneoplastic syndromes are uncommon and have only been reported as isolated case reports or short series. Here, we present a patient with Hodgkin's lymphoma with symptoms of bilateral lower extremity weakness and loss of sensation before the start of therapy, who was eventually diagnosed as having motor and sensory axonal neuropathy. Keywords: Guillain-Barre syndrome, Hodgkin's lymphoma, paraneo-plastic syndrome

Source Citation

Source Citation
Al, Isik Odaman, et al. "Hodgkin lenfomali bir hastada varyant Guillain-Barre sendromu: AMSAN/Variant Guillain-Barre syndrome in a patient with Hodgkin lymphoma: AMSAN." Turkish Pediatrics Archive, vol. 53, no. 4, Dec. 2018, pp. 263+. Accessed 19 Aug. 2022.
  

Gale Document Number: GALE|A582693716